intermediate filaments

intermediate filaments
A class of cytoplasmic filaments of animal cells so named originally because their diameter (nominally 10nm) in muscle cells was intermediate between thick and thin filaments. Unlike microfilaments and microtubules, the protein subunits of intermediate filaments show considerable diversity and tissue specificity. See cytokeratins, desmin, glial fibrillary acidic protein, neurofilament proteins, nestin and vimentin;

Dictionary of molecular biology. 2004.

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  • intermediate filaments — intermediate filaments. См. промежуточные микрофиламенты. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • intermediate filaments — a class of cytoplasmic filaments, 8–11 nm in diameter, that predominantly act as structural components of the cytoskeleton and also allow various movements in cellular processes. Different types contain different, tissue specific proteins; see… …   Medical dictionary

  • intermediate filaments — (in ter me de it fil ah ments) Small protein filaments, about 8 to 10 nm in diameter, in the cytoplasmic matrix of eucaryotic cells that are important in cell structure …   Dictionary of microbiology

  • Intermediate filament — Intermediate filaments (IFs) are cytoskeletal structures formed by members of a family of related proteins called keratin. Intermediate filaments have a diameter of 12 nanometers, which is between that of actin (microfilaments) and microtubules.… …   Wikipedia

  • filaments — See thick filaments, thin filaments, intermediate filaments, and microfilaments …   Dictionary of molecular biology

  • vimentin filaments — intermediate filaments composed of vimentin, found in a variety of cells derived from embryonic mesenchyme; they act as cytoskeletal support structures, play a role in mitosis, and are clustered particularly around the nucleus, probably helping… …   Medical dictionary

  • keratin filaments — intermediate filaments composed of cytokeratins; they are usually heteropolymers formed from one acidic and one basic cytokeratin and are present in most epithelial cells. The cytokeratin composition varies in different types, states, and degrees …   Medical dictionary

  • glial filaments — Intermediate filaments of glial cells, made of glial fibrillary acidic protein …   Dictionary of molecular biology

  • desmin filaments — intermediate filaments composed of desmin, found in muscle cells; they provide a cytoskeletal framework to hold myofibrils in place and thus coordinate contraction of the cells …   Medical dictionary

  • glial filaments — intermediate filaments composed of glial fibrillary acidic protein, found in nonneuronal cells of the central nervous system, particularly astrocytes; they provide a framework for the cells and their cytoplasmic processes …   Medical dictionary

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